Concepedia

Dual PPAR-α and -γ activators derived from novel benzoxazinone containing thiazolidinediones having antidiabetic and hypolipidemic potential

Gurram R. Madhavan, Ranjan Chakrabarti, K. Anantha Reddy, B. M. Rajesh, V. Balraju, P. Bheema Rao, Rukkumani Rajagopalan, Javed Iqbal

Bioorganic & Medicinal Chemistry · 2005 · 77 citations · 7 references

DOI

Concepts

References

7

PPARalpha and PPARgamma activators direct a distinct tissue‐specific transcriptional response via a PPRE in the lipoprotein lipase gene.

Kristina Schoonjans, Julia Peinado‐Onsurbe, Anne‐Marie Lefebvre et al. · The EMBO Journal · 1996 · 1.2K citations · Full text

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Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ

Andrew C. Li, Christoph J. Binder, Alejandra Gutierrez et al. · Journal of Clinical Investigation · 2004 · 566 citations

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Insulin Resistance in Genetically Obese, Hyperglycemic Mice

Saul Genuth, Ronald J. Przybylski, David M. Rosenberg · Endocrinology · 1971 · 119 citations

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New Antianginal Nitro Esters with Reduced Hypotensive Activity. Synthesis and Pharmacological Evaluation of 3-[(Nitrooxy)alkyl]-2H-1,3-benzoxazin-4(3H)-ones

Francesca Benedini, Giorgio Bertolini, Roberta Cereda et al. · Journal of Medicinal Chemistry · 1995 · 90 citations

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Role of PPAR in the Pharmacological Regulation of Lipoprotein Metabolism by Fibrates and Thiazolidinediones

Bart Staels, Johan Auwerx · Current Pharmaceutical Design · 1997 · 83 citations · Full text

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