Concepedia

Publication | Open Access

<scp>IL</scp>‐33 drives airway hyper‐responsiveness through <scp>IL</scp>‐13‐mediated mast cell: airway smooth muscle crosstalk

DOIFull Paper Access

159

Citations

45

References

2015

Year

Davinder Kaur, Elisabeth Calderón‐Gómez, Camille Doe, Rachid Berair, Lucy Woodman, Ruth Saunders, Fay Hollins, Felicity R. A. J. Rose, Yassine Amrani, Richard May,
Allergy

Abstract

IL-33 directly promotes mast cell activation and ASM wound repair but indirectly promotes ASM contraction via upregulation of mast cell-derived IL-13. This suggests that IL-33 may present an important target to modulate mast cell-ASM crosstalk in asthma.

References

YearCitations

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