Concepedia

Phenylethyl-substituted pyrimido[2,1-f]purinediones and related compounds: Structure–activity relationships as adenosine A1 and A2A receptor ligands

Anna Drabczyńska, Christa E. Müller, Anke C. Schiedel, Britta Schumacher, J. Karolak‐Wojciechowska, Andrzej Fruziñski, Weronika Zobnina, Olga Yuzlenko, Katarzyna Kieć‐Kononowicz

Bioorganic & Medicinal Chemistry · 2007 · 42 citations · 39 references

Open access

Concepts

MedicineMedicinal ChemistryPharmacologyMolecular PharmacologyStructure-activity RelationshipsSynthetic Medicinal ChemistryLigand BindingMolecular Targets Of DrugsAdenosine Receptor SignalingAdenosine TriphosphatasesPurine ChemistryPyrimidine AnalogsPyrimidine AnaloguesPyrimidine ChemistryReceptor-specific Ligands

References

39

The Use of Diethyl Azodicarboxylate and Triphenylphosphine in Synthesis and Transformation of Natural Products

Oyo Mitsunobu · Synthesis · 1981 · 4.1K citations

Natural Sciences, Biochemistry, Chemistry +8

Alexander Golbraikh, Alexander Tropsha · Journal of Molecular Graphics and Modelling · 2002 · 3.7K citations

The Problem of Overfitting

Douglas M. Hawkins · Journal of Chemical Information and Computer Sciences · 2003 · 2.4K citations

Natural Sciences, Chemistry, Chemical Kinetics +5

Antiepileptic Drug Development: II. Anticonvulsant Drug Screening

Ronald L Krall, J. K. Penry, B. G. White et al. · Epilepsia · 1978 · 823 citations

Medicine, Pharmacology, Clinical Pharmacology +12

Assessing Model Fit by Cross-Validation

Douglas M. Hawkins, Subhash C. Basak, Denise Mills · Journal of Chemical Information and Computer Sciences · 2003 · 762 citations

Pharmacy, Medicinal Chemistry, Drug Design +15