The dopamine D4/D2 receptor antagonist affinity ratio as a predictor of anti-aggression medication efficacy

Relationship Between Dopamine D₂ Occupancy, Clinical Response, and Side Effects: A Double-Blind PET Study of First-Episode Schizophrenia

Shitij Kapur, Robert B. Zipursky, Corey Jones et al. · American Journal of Psychiatry · 2000 · 1.1K citations

Medicine, Pharmacology, Psychiatry +17

Multiple dopamine D4 receptor variants in the human population

Hubert H.M. Van Tol, Caren M. Wu, Hong‐Chang Guan et al. · Nature · 1992 · 967 citations

Life Sciences, Genetics, Molecular Genetics +11

Modulation of Intracellular Cyclic AMP Levels by Different Human Dopamine D4 Receptor Variants

Vida Asghari, Suparna Sanyal, Saskia Buchwaldt et al. · Journal of Neurochemistry · 1995 · 862 citations

Medicine, Neurobiology, Pharmacology +17

Risperidone in the Treatment of Disruptive Behavioral Symptoms in Children With Autistic and Other Pervasive Developmental Disorders

Sarah Shea, Atilla Turgay, Alan Carroll et al. · PEDIATRICS · 2004 · 568 citations

Medicine, Pharmacology, Pharmacotherapy +16

Evidence of positive selection acting at the human dopamine receptor D4 gene locus

Yuan-Chun Ding, Han-Chang Chi, Deborah Grady et al. · Proceedings of the National Academy of Sciences · 2001 · 501 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17