Placental and mammary transfer of sulphasalazine.

Abstract

This dramatic but rare fatal complication of mitral valve disease should not be dismissed as a mere academic curiosity.With increasing use of slow-release potassium tablets it may become more common.One of the patients described by Whitney and Croxon died of gastro- intestinal haemorrhage and two of their patients had sufficient dysphagia to need feeding jejunostomies.In view of all this it seems desirable to use effervescent potassium chloride or potassium chloride mixture rather than potassium chloride tablets in patients with chronic mitral valve disease complicated by left atrial dilation.