Error in medicine.

TLDR

Medical and nursing students have long been taught Florence Nightingale’s dictum of “first, do no harm.” The authors analyzed cardiac arrest cases at a teaching hospital to assess preventability. Their findings indicate that a substantial proportion of hospitalized patients suffer iatrogenic injuries—approximately one‑third overall, with a significant fraction serious or fatal—and that 64 % of cardiac arrests were preventable, largely due to inappropriate drug use.

Abstract

FOR YEARS, medical and nursing students have been taught Florence Nightingale's dictum—first, do no harm. 1 Yet evidence from a number of sources, reported over several decades, indicates that a substantial number of patients suffer treatment-caused injuries while in the hospital. 2-6 In 1964 Schimmel 2 reported that 20% of patients admitted to a university hospital medical service suffered iatrogenic injury and that 20% of those injuries were serious or fatal. Steel et al 3 found that 36% of patients admitted to a university medical service in a teaching hospital suffered an iatrogenic event, of which 25% were serious or life threatening. More than half of the injuries were related to use of medication. 3 In 1991 Bedell et al 4 reported the results of an analysis of cardiac arrests at a teaching hospital. They found that 64% were preventable. Again, inappropriate use of drugs was the leading cause of