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7,8-Disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range

Alfonso Maresca, Andrea Scozzafava, Claudiu T. Supuran

Bioorganic & Medicinal Chemistry Letters · 2010 · 162 citations · 22 references

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22

The Carbon Dioxide Hydration Activity of Carbonic Anhydrase

Raja G. Khalifah · Journal of Biological Chemistry · 1971 · 1.9K citations · Full text

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Carbonic anhydrase inhibitors

Claudiu T. Supuran, Andrea Scozzafava, Angela Casini · Medicinal Research Reviews · 2002 · 1.4K citations

, , +12

Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH

Johanna Chiche, Karine Ilc, Julie Laferrière et al. · Cancer Research · 2008 · 746 citations

, , +17

Hypoxia activates the capacity of tumor‐associated carbonic anhydrase IX to acidify extracellular pH

Eliška Švastová, Alžbeta Hulı́ková, Monika Rafajová et al. · FEBS Letters · 2004 · 707 citations · Full text

, , +17

Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

Vincenzo Alterio, Mika Hilvo, Anna Di Fiore et al. · Proceedings of the National Academy of Sciences · 2009 · 519 citations · Full text

, , +17