A General and Versatile Method for CC Cross‐Coupling Synthesis of Conjugated Enynes: One‐Pot Sequence Starting from Carbonyl Compounds

Abstract

Ultimate coupling partners: Widely available enolizable aldehydes and ketones undergo Sonogashira cross-coupling with other carbonyl compounds to give conjugated enynes in a newly devised general method (see scheme; NfF=nonafluorobutane-1-sulfonyl fluoride). The synthetic protocol comprises at least four operating steps, which are carried out in one pot using common reagents, catalysts, and additives. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z504594_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.