Polyarteritis and Acute Post-streptococcal Glomerulonephritis

Abstract

Article1 July 1964Polyarteritis and Acute Post-streptococcal GlomerulonephritisCHRISTOPHER C. FORDHAM III, M.D., F.A.C.P., FRANKLIN H. EPSTEIN, M.D., WILLIAM D. HUFFINES, M.D., JOHN T. HARRINGTON, M.D.CHRISTOPHER C. FORDHAM III, M.D., F.A.C.P.Search for more papers by this author, FRANKLIN H. EPSTEIN, M.D.Search for more papers by this author, WILLIAM D. HUFFINES, M.D.Search for more papers by this author, JOHN T. HARRINGTON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-61-1-89 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis paper reports on three patients who presented clinical and laboratory evidence suggesting acute post-streptococcal glomerulonephritis, each of whom was found to have polyarteritic lesions.CASE REPORTSCASE 1R. M.: This 21-year-old Negro man was admitted on April 2, 1963. He had been well until 3 weeks previously when he had a severe sore throat that lasted for 1 week and cleared without treatment. One week before entry he noted swelling and pain about several joints, lasting for 2 or 3 days, and 4 days before admission he experienced lower abdominal pain, anorexia, nausea, and vomiting. The next day...References1. ZEEK PM: Periarteritis nodosa: a critical review. Amer. J. Clin. Path. 22: 777, 1952. CrossrefMedlineGoogle Scholar2. CHURGSTRAUSS JL: Allergic granulomatosis, allergic angiitis, and periarteritis nodosa. Amer. J. Path. 27: 277, 1951. MedlineGoogle Scholar3. RICH AR: The role of hypersensitivity in periarteritis nodosa. Bull. Hopkins Hosp. 71: 123, 1942. Google Scholar4. KIPKIEJOHNSON GFDS: Possible pathogenic mechanisms responsible for human periarteritis nodosa, as suggested by occurrence of 2 instances of this disease in association with glomerulonephritis. Arch. Path. 51: 387, 1951. Google Scholar5. DAWSON D: Acute periarteritis nodosa with chronic glomerulonephritis. Arch. Path. 68: 651, 1959. MedlineGoogle Scholar6. HARRISONLOUGHRIDGEMILNE CVLWMD: Acute oliguric renal failure in acute glomerulonephritis and periarteritis nodosa. Quart. J. Med. 33: 39, 1964. MedlineGoogle Scholar7. ROSESPENCER GAH: Polyarteritis nodosa. Quart. J. Med. 26: 43, 1957. MedlineGoogle Scholar8. MUIRHEADVANATTAGROLLMAN EEJA: Hypertensive cardiovascular disease: an experimental study of tissue changes in bilaterally nephrectomized dogs. Arch. Path. 48: 234, 1949. Google Scholar9. MUIRHEADGROLLMAN EEA: Acute renal insufficiency in man manifesting the arterial necrosis observed in dogs following bilateral nephrectomy. Amer. J. Med. 10: 780, 1951. CrossrefMedlineGoogle Scholar10. KUSHNER DS: Natural history and therapy of acute glomerulonephritis. Advances Intern. Med. 11: 75, 1962. MedlineGoogle Scholar11. : Treatment of Polyarteritis Nodosa with Cortisone: Results after three years. Brit. Med. J. 1: 1399, 1960. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chapel Hill, North Carolina, and New Haven, ConnecticutFrom the Departments of Medicine and Pathology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, and the Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.This study was supported in part by United States Public Health Service grants, NIH, National Heart Institute HE-06350, and NIH5 R0l-HE-01301-02.Dr. Huffines is a John and Mary R. Markle Scholar in Academic Medicine.Requests for reprints should be addressed to Christopher C. Fordham III, M.D., The University of North Carolina, Chapel Hill, North Carolina. 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