Serial Creatine Kinase‐MB Results Are a Sensitive Indicator of Acute Myocardial Infarction in Chest Pain Patients with Nondiagnostic Electrocardiograms: The Second Emergency Medicine Cardiac Research Group Study

Abstract

Serial CK-MB monoclonal antibody mass measurements in the ED can identify MI patients with initially nondiagnostic ECGs. CK-MB sensitivity significantly increases over 3 hours of observation of stable chest discomfort patients in the ED; it also increases as a function of the total interval from onset until enzyme measurement.