Can Low-Dose Unenhanced Chest CT Be Used for Follow-Up of Lung Nodules?

Abstract

For lung nodules≤200 mm3 (approximately 8 mm) the measured volume on low-dose unenhanced CT is significantly lower when compared with standard-dose contrast-enhanced CT. This effect is likely due to contrast administration rather than other imaging parameters, which should be taken into account in the follow-up of lung nodules because growth can remain undetected or doubling time underestimated.