Glutamate neurotoxicity is associated with nitric oxide-mediated mitochondrial dysfunction and glutathione depletion

Glutamate neurotoxicity and diseases of the nervous system

Dennis W. Choi · Neuron · 1988 · 8K citations

Neurodegenerative Diseases, Neurophysiology, Neuropharmacology +8

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

Joseph S. Beckman, ThomasJ Beckman, Jake Y. Chen et al. · Proceedings of the National Academy of Sciences · 1990 · 7K citations · Full text

Inflammation, Peroxynitrite Decomposition, Redox Signaling +15

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

Xuesong Liu, Caryn Naekyung Kim, Jie Yang et al. · Cell · 1996 · 5.2K citations · Full text

Apoptotic Program, Biochemistry, Medicine +11

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

John Garthwaite, Sarah L. Charles, Russ Chess‐Williams · Nature · 1988 · 2.6K citations

Intercellular Messenger, Neurophysiology, Physiology +9

Peroxynitrite oxidation of sulfhydryls.

Rafael Radí, Joseph S. Beckman, Ken Bush et al. · Journal of Biological Chemistry · 1991 · 2.5K citations · Full text