Concepedia

Comparison of two HPLC techniques for monitoring enantioselective reactions for the resolution of (R,S)-ibuprofen: Chiral HPLC vs achiral HPLC linked to an optical rotation detector

Amélie Ducret, Michael Trani, Pierre Pepin, Robert Lortie

Biotechnology Techniques · 1995 · 10 citations · 8 references

Concepts

PharmacyChemistryPharmaceutical AnalysisAnalytical ChemistryChromatographic AnalysisChiral ChromatographyChiral SeparationChromatographic Analysis Of PharmaceuticalsChromatographyLiquid ChromatographyAnalytical Chiral ChromatographyChiral ColumnsChiral High-performance Liquid ChromatographyChiral Liquid ChromatographyChiral Resolution AssessmentChromatographic Chiral SeparationEnantioselective DetectionOptical Rotation Measurement

References

8

Effects of Anti-inflammatory Drugs on Prostaglandin Biosynthesis

R.J. Flower, R Gryglewski, K. HERBACZŃSKA-CEDRO et al. · Nature New Biology · 1972 · 476 citations

Life Sciences, Biochemistry, Pharmacology +14

Pharmacological differences between the optical isomers of ibuprofen: evidence for metabolic inversion of the (—)-isomer

S. S. Adams, P. Bresloff, C. G. Mason · Journal of Pharmacy and Pharmacology · 1976 · 386 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Relationship between inhibition of prostaglandin synthesis and drug efficacy: Support for the current theory on mode of action of aspirin-like drugs

Rosemarie Tomlinson, Howard J. Ringold, M.C. Qureshi et al. · Biochemical and Biophysical Research Communications · 1972 · 206 citations

Medicine, Pharmacology, Pharmacotherapy +12

A rapid spectrophotometric assay for prostaglandin synthetase: Application to the study of non-steroidal antiinflammatory agents

C. Takeguchi, Charles J. Sih · Prostaglandins · 1972 · 127 citations

Life Sciences, Biochemistry, Pharmacology +10

STEPHEN STINSON · Chemical & Engineering News · 1994 · 99 citations

Pharmacy, Medicinal Chemistry, Pharmacology +6