One‐pot synthesis of polyfunctionalized pyrans catalyzed by basic ionic liquid in aqueous media

Abstract

Abstract magnified image An efficient and convenient method for the synthesis of polyfunctionalized 4 H ‐pyrans has been achieved through the one‐pot condensation of aromatic aldehydes, malononitrile, and 4‐hydroxycoumarin, phenols or active methylene carbonyl compounds such as 1, 3‐cyclohexanedione and dimedone in the presence of 1‐butyl‐3‐methyl imidazolium hydroxide ([bmim]OH) as catalyst in aqueous media. This method offers several advantages short reaction time, high yields, and simple procedure. J. Heterocyclic Chem., (2009).