Treatment of polyarteritis nodosa and microscopic polyangiitis without poor‐prognosis factors: A prospective randomized study of one hundred twenty‐four patients

Abstract

For patients with PAN or MPA with an FFS of 0, overall 5-year survival was good, but first-line corticosteroid treatment was able to achieve and maintain remission in only about half of the patients, and 40% of the patients required additional immunosuppressive therapy. Azathioprine or pulse cyclophosphamide was fairly effective for treating corticosteroid-resistant disease or major relapses.