Synthesis of Substituted 1,2,3,4-Tetrahydro-6-methyl-2-thioxo-5-pyrimidinecarboxylic Acid Esters

Abstract

AbstacI-Substituted 1.2,3Atewhydro-6-methyl-2-thioxo-5-pyrimidinccarboxylic acid esters are prepared in high o v d l yield from 2-methylene-3-oxobutanoic acid esters and 2-(4methoxybenzyl)-2-thiopseudoma hydrochloride.It h a been reported that 1 .2 .3 .4 -t e t r a h y h b m e t h y l -2 -t h i o x o -5 -p y c acid esters 1 (X = s)' can