The Journal of Clinical Endocrinology & Metabolism · 1980 · 91 citations · 13 references
MedicineEndocrinologyOncologyCalcium HomeostasisEndocrine OncologyGenitourinary OncologyCalcium EndocrinologyEndocrine Regulation Of CalciumParathyroid DisordersParathyroid Gland PhysiologyParathyroid Hormone PhysiologyParathyroid Hormone RegulationCalcium Homeostasis AssessmentHypercalcemia Of MalignancyParathyroid Cell FunctionParathyroid DysfunctionParathyroid Function AssessmentParathyroid Hormone AssessmentParathyroid Hormone BiologyParathyroid Pathology
Total and nephrogenous urinary cyclic AMP (cAMP), serum Parathyroid Hormone (PTH) and ionized calcium (Ca) levels were determined in 8 normal subjects, and 16 normocalcemic and 9 hypercalcemic patients with lung cancer. Total and nephrogeneous cAMP levels were significantly increased in both normocalcemic and hypercalcemic lung cancer patients, as compared to normal subjects. There was no significant correlation between serum PTH and total or nephrogenous cAMP in the cancer group. The factors responsible for the elevated nephrogenous cAMP in the lung cancer patients are not known.
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