Incremental reductions of positive charge within the S4 region of a voltage-gated K+ channel result in corresponding decreases in gating charge

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.1K citations · Full text

Dna, Engineering, Dna Analysis +20

A quantitative description of membrane current and its application to conduction and excitation in nerve

A. L. Hodgkin, A. F. Huxley · The Journal of Physiology · 1952 · 22.9K citations · Full text

Hyperpolarization (Biology), Neurophysiology, Physiology +11

Ionic channels of excitable membranes

General Pharmacology The Vascular System · 1985 · 7K citations

Membrane Transport, Physiology, Ion Channels +6

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

Gray D. Shaw, Robert Kamen · Cell · 1986 · 4.1K citations

Transcriptional Regulation, Untranslated Region, Natural Sciences +10

Ionic Channels of Excitable Membranes

R. D. Keynes · Trends in Neurosciences · 1985 · 2.6K citations

Membrane Transport, Physiology, Ion Channels +6