Altered Alkaloid Pattern in Dark Grown Seedlings of Catharanthus roseus. The Isolation and Characterization of 4-Desacetoxyvindoline: A Novel Indole Alkaloid and Proposed Precursor of Vindoline

Abstract

d i n r e l a t i v e l y h i g h and even r a t e s of germination.A n a l y s i s o f a l k a l o i d s from t h e cotyledons o f 6 -9 day o l d dark grown seedlings l e d t o t h e i d e n t i f i c a t i o n o f tabersonine, 16-methoxytabersonine, and catharanthine as r e l a t i v e l y major components w h i l e v i n d o l i n e , d e a c e t y l v i n d o l i n e , 4-desacetoxyvindoline and 16-hydroxytabersonine were i d e n t i f i e d as minor components.Subjecting dark grown seedlings t o l i g h t