Thimerosal induces endothelium-dependent vascular smooth muscle relaxations by interacting with thiol groups

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

Life Sciences, Cell Biology, Physiology +15

Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta.

William Martin, G. Villani, D Jothianandan et al. · Journal of Pharmacology and Experimental Therapeutics · 1985 · 1.3K citations

Medicine, Pharmacology, Physiology +8

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

Stuart Bunting, Salvador Moncada, John R. Vane et al. · Prostaglandins · 1976 · 955 citations

Medicine, Physiology, Signal Transduction +11

The nature of endothelium-derived vascular relaxant factor

Tudor M. Griffith, D. H. Edwards, Malcolm Lewis et al. · Nature · 1984 · 585 citations

Medicine, Pharmacology, Physiology +7

Role of endothelial cells in relaxation of isolated arteries by bradykinin.

P. Cherry, Robert F. Furchgott, John V. Zawadzki et al. · Proceedings of the National Academy of Sciences · 1982 · 426 citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +11