The predictive value of p53 and p33^<i>ING1b</i> in patients with Dukes'C colorectal cancer

Abstract

In patients with Dukes'C colorectal cancer who underwent curative surgical resection of the primary tumour, followed by 5-FU-based adjuvant chemotherapy, p53 mutation status as assessed by gene sequencing is a significant predictor of overall and metastasis-free survival.