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20-Hydroxyeicosatetraenoic Acid Mediates Isolated Heart Ischemia/Reperfusion Injury by Increasing NADPH Oxidase-Derived Reactive Oxygen Species Production

DOIFull Paper Access

42

Citations

24

References

2013

Year

Yong Hwan Han, Huiying Zhao, Hong Tang, Xinyu Li, Jiang Tan, Qinghua Zeng, Chengwen Sun
Circulation Journal

Abstract

All of the results demonstrated that in isolated rat hearts 20-HETE stimulates NADPH oxidase-derived superoxide production, which aggravates I/R-induced myocardial injury via a PKC-dependent mechanism.

References

YearCitations

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