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F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103
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Dual InhibitorMolecular PharmacologyMedicinal ChemistryVivo Antitumour ActivityMedicinePathologyPharmacotherapyAnti-cancer AgentF 11782Drug DevelopmentPharmacologyPharmaceutical ChemistryDrug DiscoveryDrug Resistance
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