Concepedia

Mast Cell Disease

Sharat Damodar, Colin Noel John, Gayathri Gopalakrishnan, Sheila Nair, Rekha Samuel, Mathew Thomas, Devi Prasad Shetty

Journal of Pediatric Hematology/Oncology · 2006 · 19 citations · 4 references

DOI

Concepts

Abstract

Mast cell disease (MCD) is a clonal disorder of the mast cell and its precursor cells. Cardiac surgery in MCD is rarely described. We report an unusual case of a 14-year-old girl who was admitted for atrial septal defect closure and incidentally found to have hepatosplenomegaly with lymphadenopathy who underwent a successful open-heart surgery, after a diagnosis of MCD.

References

4

CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy

Animesh Pardanani, Rhett P. Ketterling, Stephanie R. Brockman et al. · Blood · 2003 · 396 citations · Full text

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A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib

Cem Akin, Gerard Fumo, Akif Selim Yavuz et al. · Blood · 2003 · 358 citations · Full text

, , +9

Cladribine therapy for systemic mastocytosis

Hanneke C. Kluin‐Nelemans · Blood · 2003 · 247 citations · Full text

, , +8

Systemic mastocytosis presenting as profound cardiovascular collapse during anaesthesia

S. T. A. Vaughan, Gabriel Jones · Anaesthesia · 1998 · 92 citations · Full text

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