Concepedia

Regioselective<i>C</i>2 Sulfonylation of Indoles Mediated by Molecular Iodine

Praewpan Katrun, Mueangkaew Charoensak, Manat Pohmakotr, Vichai Reutrakul, Thaworn Jaipetch, Darunee Soorukram, Chutima Kuhakarn

The Journal of Organic Chemistry · 2014 · 111 citations · 35 references

DOI

Abstract

A facile and general method for regioselective C2 sulfonylation reaction of indoles mediated by iodine is described. The 2-sulfonylated products were obtained up to 96% yield under mild reaction conditions (room temperature, 2 h).

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