Phenylnaphthalene Compounds from the Subterranean Part of<i>Vitex rotundifolia</i>and Their Antibacterial Activity Against Methicillin-Resistant<i>Staphylococcus aureus</i>

Abstract

A careful investigation of the subterranean part of Vitex rotundifolia has shown that this plant contains five novel lignans having a 1-phenylnaphthalene-type skeleton together with four known lignans. These structures were elucidated on the basis of spectroscopic data. Furthermore, some of the isolated compounds showed antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).