Effects of tyrosyl-arginine (kyotorphin), a new opioid dipeptide, on single neurons in the spinal dorsal horn of rabbits and the nucleus reticularis paragigantocellularis of rats

A novel analgesic dipeptide from bovine brain is a possible Met-enkephalin releaser

Hiroshi Takagi, Hirohito Shiomi, Hiroshi Ueda et al. · Nature · 1979 · 258 citations

Medicine, Neuroscience, Pharmacology +16

Analgesia induced by microinjection of morphine into, and electrical stimulation of, the nucleus reticularis paragigantocellularis of rat medulla oblongata

A Akaike, Takashi Shibata, Masamichi Satoh et al. · Neuropharmacology · 1978 · 186 citations

Life Sciences, Neuroscience, Pharmacology +16

Morphine-like analgesia by a new dipeptide, L-Tyrosyl-L-Arginine (kyotorphin) and its analogue

Hiroshi Takagi, Hirohito Shiomi, Hiroshi Ueda et al. · European Journal of Pharmacology · 1979 · 167 citations

Medicine, Anesthesiology, Pharmacology +13

Excitation by morphine and enkephalin of single neurons of nucleus reticularis paragigantocellularis in the rat: a probable mechanism of analgesic action of opioids

Masamichi Satoh, Akinori Akaike, Hiroshi Takagi · Brain Research · 1979 · 88 citations

Life Sciences, Neuroscience, Pharmacology +16

Selective and non-selective inhibition by enkephalins and noradrenaline of nociceptive response of lamina V type neurons in the spinal dorsal horn of the rabbit

Masamichi Satoh, Shin-Ichi Kawajiri, Yojiro Ukai et al. · Brain Research · 1979 · 62 citations

Life Sciences, Neurobiology, Neuroscience +17