Adrenergic Modulation of Erythropoiesis Following Severe Injury Is Mediated Through Bone Marrow Stroma

Abstract

There is a substantial and persistent hyperadrenergic state seen after severe injury that may last for up to a week. Adrenergic agonists have a clear stimulatory effect on the growth of primitive erythroid precursors in normal BM. The adrenergic stimulus appears to be mediated via BM stroma.