Down-regulation of cardiac apelin system in hypertrophied and failing hearts: Possible role of angiotensin II–angiotensin type 1 receptor system

Isolation and Characterization of a Novel Endogenous Peptide Ligand for the Human APJ Receptor

Kazuhiko Tatemoto, Masaki Hosoya, Yugo Habata et al. · Biochemical and Biophysical Research Communications · 1998 · 1.7K citations

Medicine, Medicinal Chemistry, Pharmacology +10

Hydrolysis of Biological Peptides by Human Angiotensin-converting Enzyme-related Carboxypeptidase

Chad Vickers, Paul Hales, Virendar K. Kaushik et al. · Journal of Biological Chemistry · 2002 · 1.4K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11

Brian F. O’Dowd, Michael Heiber, Audrey Chan et al. · Gene · 1993 · 840 citations

Life Sciences, Genetics, Molecular Genetics +5

Apelin, the Novel Endogenous Ligand of the Orphan Receptor APJ, Regulates Cardiac Contractility

István Szokodi, Pasi Tavi, Gábor Földes et al. · Circulation Research · 2002 · 617 citations

Life Sciences, Pharmacology, Physiology +11

Molecular and Functional Characteristics of APJ

Masaki Hosoya, Yuji Kawamata, Shoji Fukusumi et al. · Journal of Biological Chemistry · 2000 · 476 citations · Full text

Life Sciences, Biochemistry, Pharmacology +11