Elimination of Thallium in Rats as Influenced by Prussian Blue and Sodium Chloride

Abstract

Abstract The effect of Prussian Blue in protecting rats against lethal doses of thallium was investigated. Treatment with Prussian Blue increased the survival of rats from 0% to 50%. The elimination rate of thallium was increased in all the tissues studied, including the brain. Faecal thallium excretion was increased about three–fold. Treatment with hypertonic sodium chloride improved the short–term survival but the total mortality was unchanged.