Concurrent Alterations in <i>TERT</i> , <i>KDM6A</i> , and the BRCA Pathway in Bladder Cancer

Abstract

This study is the first to identify frequent BAP1 and BRCA pathway alterations in bladder cancer, show TERT promoter alterations are independent of other bladder cancer gene alterations, and show KDM6A loss is a driver of the bladder cancer phenotype.