A New Model for Studying the Revascularization of Skin Grafts In Vivo: The Role of Angiogenesis

Abstract

This new model allows for repetitive analysis of the microcirculation during skin graft healing. It provides ideal in vivo conditions to further delineate the exact mechanisms of blood vessel interconnection during the complex process of angiogenesis, and may also allow study of the vascularization of tissue-engineered skin substitutes.