Angewandte Chemie International Edition · 1998 · 90 citations · 0 references
Natural SciencesChemistryCatalysisOrganic ChemistryCatalyst DesignCatalytic MechanismsCross-coupling ReactionsHeterocycle SynthesisRedox CatalysisAlkyne Cycloaddition ReactionsLigand SelectivityMild Reaction Conditions
No electron-withdrawing or electron-releasing substituents are necessary for the substrates in the rhodium-catalyzed [4+2] cycloaddition reaction between a vinylallene and an ordinary alkyne under mild conditions [Eq. (1)]. The use of the strongly electron-accepting P[OCH(CF3)2]3 ligand affords the optimal rhodium catalyst. cod = 1,5-cyclooctadiene.