Modeling of p38 mitogen-activated protein kinase inhibitors using the Catalyst™ HypoGen and k-nearest neighbor QSAR methods

The Importance of Being Earnest: Validation is the Absolute Essential for Successful Application and Interpretation of QSPR Models

Alexander Tropsha, Paola Gramatica, Vijay K. Gombar · QSAR & Combinatorial Science · 2003 · 2.2K citations

Pharmacy, Medicinal Chemistry, Drug Design +16

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1

Ana Cuenda, J.B. Rouse, Yair N. Doza et al. · FEBS Letters · 1995 · 2.1K citations

Life Sciences, Molecular Biology, Pharmacology +14

Rational selection of training and test sets for the development of validated QSAR models

Alexander Golbraikh, Min Shen, Zhiyan Xiao et al. · Journal of Computer-Aided Molecular Design · 2003 · 715 citations

Pharmacy, Medicinal Chemistry, Drug Design +12

The search for physiological substrates of MAP and SAP kinases in mammalian cells

P P Cohen · Trends in Cell Biology · 1997 · 537 citations

Life Sciences, Biochemistry, Molecular Biology +12

Predictive QSAR modeling based on diversity sampling of experimental datasets for the training and test set selection

Alexander Golbraikh, Alexander Tropsha · Journal of Computer-Aided Molecular Design · 2002 · 493 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15