Archives of Disease in Childhood · 1974 · 70 citations · 7 references
MedicineGeneticsUrologyGenitourinary RadiologyPediatric NephrologyPediatric UrologyCongenital Genitourinary AnomaliesCongenital Renal AnomaliesCongenital Urinary Tract AnomaliesAnatomical Urinary Tract AbnormalitiesAutosomal Dominant InheritanceCongenital Urinary AnomaliesCongenital Urogenital MalformationsRoutine ScreeningUrinary Tract DisordersUrinary Tract MalformationsVariable Penetrance
The incidence of a duplex urinary tract was determined in the parents and sibs of 30 index patients with either unilateral or bilateral bifid or double ureters. Our results support the hypothesis that a duplex urinary tract is inherited by an autosomal dominant gene of variable penetrance. Routine screening by limited intravenous pyelography of sibs of index patients is recommended in order to detect a duplex urinary tract before the onset of complications.
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