Dermatologica · 2009 · 11 citations · 0 references
Life SciencesBiologyGeneticsCraniofacial GeneticsHuman GeneticsMedical GeneticsGenetic DisordersMendelian DisordersMendelian InheritanceTwin StudiesAutosomal Dominant InheritanceDizygotic TwinsFamilial Inheritance PatternsMonozygotic Twins
This is the first case report of bilateral naevus comedonicus seen in a pair of twins in Singapore. 3 other family members were similarly affected. Though both sexes were affected, there were more males affected as compared to females. Recent reports support a familial inheritance. Our pedigree showed an autosomal dominant inheritance. The extensive involvement seen in the twins suggest that they may be homozygous for this condition.