Angewandte Chemie International Edition · 2002 · 100 citations · 25 references
Natural SciencesChemistryOrganic ChemistryChemical BondingCross-coupling ReactionsMolecular Formation PathwaysOrganic SynthesisRadical ReactionsRetrosynthetic AnalysisBond Formation MechanismsFree Radical AdditionFree Radical OxidationRadical Mediated C - C Bond FormationRadical Reaction Mechanisms
Primary alkyl radicals are generated highly efficiently and reliably from alkyl allyl sulfone precursors. The latter are effective in tin-free radical CC-bond formations, including cyanation, vinylation, and allylation (see scheme; V-40=1,1′-azobis(cyclohexane-1-carbonitrile).
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