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Hammerhead ribozyme against γ-glutamylcysteine synthetase sensitizes human colonic cancer cells to cisplatin by down-regulating both the glutathione synthesis and the expression of multidrug resistance proteins

Tumor Biologyγ-Glutamylcysteine SynthetaseMedicineCancer Cell BiologyHammerhead RibozymeCancer BiologyGlutathione SynthesisAnti-cancer AgentCancer TreatmentPharmacologyRadiation OncologyCancer ResearchCancer Metabolism