Publication | Open Access
Self-Organized Stable Pacemakers near the Onset of Birhythmicity
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Citations
19
References
2001
Year
Cardiac MusclePattern FormationElectrophysiological EvaluationSelf-organized Stable PacemakersPhysiologyGeneral Amplitude EquationsElectrophysiologyBifurcation TheoryPeriodic Travelling WaveChaotic MixingMedicinePacemaker SolutionsCardiologyStable Autonomous PacemakersNonlinear OscillationArrhythmia
General amplitude equations are derived for reaction-diffusion systems near the soft onset of birhythmicity described by a supercritical pitchfork-Hopf bifurcation. Using these equations and applying singular perturbation theory, we show that stable autonomous pacemakers represent a generic kind of spatiotemporal patterns in such systems. This is verified by numerical simulations, which also show the existence of breathing and swinging pacemaker solutions. The drift of self-organized pacemakers in media with spatial parameter gradients is analytically and numerically investigated.
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