Publication | Open Access
THE HISTOCHEMICAL DEMONSTRATION OF INTESTINAL β-<scp>d</scp>-FUCOSIDASE WITH 5-BROMO-4-CHLOROINDOLE-3-yl-β-<scp>d</scp>-FUCOPYRANOSIDE
18
Citations
0
References
1967
Year
Bioorganic ChemistryGlycobiologyGastroenterologyMolecular BiologyCompetitive InhibitionPolysaccharideDigestive TractEnzymatic ModificationBiosynthesisHalogen-substituted Indolyl SubstrateGlycosylationBiochemistrySimilar Tissue EnzymesCellular EnzymologyNatural SciencesBiotechnologyCellular BiochemistryMedicineCarbohydrate-protein Interaction
Enzymatic hydrolysis of a halogen-substituted indolyl substrate for β-d-fucosidase shows a strong positive reaction in the interstitial mononuclear cells in the jejunum. This localization and the optimum pH are different from that of the analogous substrate for 3-d-galactosidase. The results of competitive inhibition of these substrates suggest that the reactions demonstrate distinct but similar tissue enzymes.