Possible Precipitation of Cerebral Thrombosis in Sickle-Cell Anemia by Hyperventilation

Abstract

Letters1 September 1973Possible Precipitation of Cerebral Thrombosis in Sickle-Cell Anemia by HyperventilationLEON M. PROTASS, M.D.LEON M. PROTASS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-79-3-451_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: A 2- to 4-minute period of voluntary hyperventilation during electroencephalography is a benign provocative procedure, of limited value, done in most laboratories. This is a report of a presumed adverse reaction in a child with sickle cell disease.An 11-year-old girl with sickle-cell disease had had episodes of left hemiparesis 1½ and 4 months earlier. On both occasions there was complete resolution of the paresis within a few days, but a left homonymous hemianopsia persisted after the second episode. Cerebral vascular thrombosis was thought to be the cause (1). A routine electroencephalogram was done. Immediately after hyperventilation,...References1. PORTNOYHERION BJ: Neurological manifestations in sickle-cell disease. With a review of the literature and emphasis on the prevalence of hemiplegia. Ann Intern Med 76:643-652, 1972 LinkGoogle Scholar2. GOTOHMEYERTAKAGI FJY: Cerebral effects of hyperventilation in man. Arch Neurol 12:410-423, 1965 CrossrefMedlineGoogle Scholar3. JENSENRUCKNAGELTAYLOR WDW: In vivo study of the sickle cell phenomenon. J Lab Clin Med 56:854-865, 1960 MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Neurology Montefiore Hospital and Medical Center Bronx, New York PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByHypoxic adaptation during development: relation to pattern of neurological presentation and cognitive disabilityElectroencephalography Hyperventilation and Stroke in Children with Sickle Cell DiseasePrognosis of Cerebral Arteriopathy in StrokeScreening Electroencephalograms in Autism Spectrum Disorders: Evidence-Based GuidelineAcute Therapy of Childhood StrokePanic DisorderHyperventilation syndromeRespiratory Acid-Base DisordersNeurological Syndromes, Management and Prognosis in Sickle-Cell Anaemia 1 September 1973Volume 79, Issue 3Page: 451-451KeywordsAdverse reactionsAnemiaElectroencephalographySickle cell diseaseThrombosis Issue Published: 1 September 1973 PDF DownloadLoading ...