Concepedia

Metastatic Merkel Cell Carcinoma With Positive Expression of Thyroid Transcription Factor-1-A Case Report

Adam Sierakowski, Khalid Al-Janabi, Helena Van Dam, Manu Sood

American Journal of Dermatopathology · 2009 · 24 citations · 20 references

DOI

Concepts

Abstract

We report on a case of metastatic Merkel cell carcinoma in a 74-year-old patient with positive staining for thyroid transcription factor-1. This represents a new immunohistochemical staining pattern for Merkel cell carcinoma and has implications regarding the accurate diagnosis of this tumor type.

References

20

Cytokeratin 20 Immunoreactivity Distinguishes Merkel Cell (Primary Cutaneous Neuroendocrine) Carcinomas and Salivary Gland Small Cell Carcinomas from Small Cell Carcinomas of Various Sites

John K. Chan, Saul Suster, Bruce M. Wenig et al. · The American Journal of Surgical Pathology · 1997 · 390 citations

, , +15

Thyroid Transcription Factor-1 Is Expressed in Extrapulmonary Small Cell Carcinomas but Not in Other Extrapulmonary Neuroendocrine Tumors

S. Nicholas Agoff, Laura W. Lamps, Abraham T Philip et al. · Modern Pathology · 2000 · 356 citations · Full text

, , +10

Value of Thyroid Transcription Factor-1 Immunostaining in Distinguishing Small Cell Lung Carcinomas From Other Small Cell Carcinomas

Nelson G. Ordóǹez · The American Journal of Surgical Pathology · 2000 · 336 citations

, , +12

Expression of thyroid transcription factor‐1 in pulmonary and extrapulmonary small cell carcinomas and other neuroendocrine carcinomas of various primary sites

H. Kaufmann, Dietel · Histopathology · 2000 · 290 citations

, , +17

Immunostaining for Thyroid Transcription Factor 1 and Cytokeratin 20 Aids the Distinction of Small Cell Carcinoma From Merkel Cell Carcinoma, But Not Pulmonary From Extrapulmonary Small Cell Carcinomas

Wah Cheuk, Man-Yee Kwan, Saul Suster et al. · Archives of Pathology & Laboratory Medicine · 2001 · 275 citations

, , +8