PLATELET AND LEUKOCYTE ADHESION IN THE MICROVASCULATURE AT THE CEREBRAL SURFACE IMMEDIATELY AFTER SUBARACHNOID HEMORRHAGE

Abstract

SAH at the skull base induced P-selectin- and oxygen radical-mediated platelet-leukocyte-endothelial cell interactions in venules at the cerebral surface. These early inflammatory and prothrombogenic responses may cause a whole-brain injury immediately after SAH.