Longitudinal Changes in Ferritin During Chronic Transfusion: A Report From the Stroke Prevention Trial in Sickle Cell Anemia (STOP)

Abstract

There was strong intrapatient correlation between serum ferritin levels and volume transfused but wide interpatient variability early during chronic transfusion therapy. Intrapatient correlation declined at transfusion volumes of more than 250 mL/kg. Direct iron store assessment is needed to determine the clinical significance of serum ferritin variability.