Prior varicella zoster virus exposure in <scp>IBD</scp> patients treated by anti‐<scp>TNF</scp>s and other immunomodulators: implications for serological testing and vaccination guidelines

Abstract

Negative history of VZV exposure is a poor predictor of seronegativity. History-positive patients may still be seronegative and exposed to VZV infection. We suggest serological testing of all IBD patients with subsequent immunisation of the seronegative patients before initiation of immunosuppressive therapy.