EGFRvIII-mediated transactivation of receptor tyrosine kinases in glioma: mechanism and therapeutic implications

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Roel G.W. Verhaak, Katherine A. Hoadley, Elizabeth Purdom et al. · Cancer Cell · 2010 · 7.7K citations · Full text

Medicine, Molecular Genetics, Oncology +12

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

Dominik Sturm, Hendrik Witt, Volker Hovestadt et al. · Cancer Cell · 2012 · 1.9K citations · Full text

Medicine, Genetics, Molecular Genetics +16

Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors

Ingo K. Mellinghoff, Maria Y. Wang, Igor Vivanco et al. · New England Journal of Medicine · 2005 · 1.4K citations · Full text

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Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC

Alexa B. Turke, Kreshnik Zejnullahu, Yi‐Long Wu et al. · Cancer Cell · 2010 · 1.1K citations · Full text

Medicine, Molecular Biology, Oncology +16

Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies

Jayne M. Stommel, Alec C. Kimmelman, Haoqiang Ying et al. · Science · 2007 · 928 citations

Medicine, Cancer Biology, Oncology +17