Prognostic significance of nuclear DNA content and proliferative activity in renal cell carcinomas: A clinicopathologic study of 58 patients using mitotic count, MIB-1 staining, and DNA cytophotometry

Abstract

In addition to tumor grade and stage, both a high MIB-1 index and a noneuploid or aneuploid DNA histogram of a given RCC have the potential to identify tumor patients with an impaired prognosis.