Electrostimulation‐induced fast‐to‐slow transitions of myosin light and heavy chains in rabbit fast‐twitch muscle at the mRNA level

Abstract

Chronic low-frequency stimulation of rabbit fast-twitch muscle induces progressive increases in slow myosin light chain mRNAs followed by an increase in the slow myosin heavy chain HCI mRNA. Therefore, the effects of chronic stimulation are more pronounced in rabbit than in rat fast-twitch muscle. The latter responds mainly with a rearrangement of its fast isomyosin pattern.