The metabolites of Trichoderma longibrachiatum. Part II The structures of trichodermolide and sorbiquinol

Abstract

Trichoderma longibrachiatum Rifai aggr. is a fungus reported to be antagonistic to the fungus Mycena citricolor, the causative agent of the American leaf spot disease of coffee. We have investigated the metabolites produced when T. longibrachiatum is grown in liquid culture and have isolated several new compounds. The structures of trichodermolide (2) and sorbiquinol (3) were determined by a combination of spectroscopic techniques, including 1 H and 13 C NMR, IR, UV, CD, ORD, and mass spectrometry, and by preparation of derivatives. Key words: Trichoderma longibrachiatum, leaf spot disease, coffee, fungal metabolites.