Genetic Association of a Cathepsin D Polymorphism and Sporadic Creutzfeldt-Jakob Disease

Abstract

Our study does not show a significant difference in genotype (p = 0.901) and allele (p = 0.509) frequencies of CTSD C224T between sporadic CJD patients and normal controls. This was the first genetic association study of CTSD in a sporadic CJD population.